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4P-15-3: ARMOR3-SV: A Phase 3, Randomized, Open Label, Multi- Center Controlled Study of Galeterone Compared With Enzalutamide in Men Expressing Androgen Receptor Splice Variant-7 mRNA Metastatic Castration-Resistant Prostate Cancer

Description

The purpose of this study is to compare galeterone to enzalutamide in men expressing androgen receptor spice variant-7 mRNA (AR-V7) in metastatic (M1) castrate resistant prostate cancer (CRPC).

Phase

Phase 3 - a treatment has shown activity against a particular disease, where it is either added to existing treatment or compared to the standard treatment.

Inclusion and Exclusion Criteria

  • Progressive metastatic (M1) disease on androgen deprivation therapy
  • Detectable AR-V7 from circulating tumors (CTCs)
  • ECOG performance status 0 or 1

  • Prior treatment with second generation anti-androgens (e.g. abiraterone, enzalutamide)
  • Prior treatment with chemotherapy for CRPC

Sites

Please contact the trial administrator to learn more about where you can participate in this trial. Please use the contact form on the right side.

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