A Phase 3b/4 Randomized Double Blind Study Of 5 Mg Of Tofacitinib With And Without Methotrexate In Comparison To Adalimumab With Methotrexate In Subjects With Moderately To Severely Active Rheumatoid Arthritis

Description

N/A

Have moderate to severe rheumatoid arthritis
On methotrexate but inadequately controlled
Subjects must not have active tuberculosis or an inadequately treated tuberculosis infection
Subjects must use contraception

Subjects who have been previously treated with adalimumab or Tofacitinib
Subjects with any current malignancy or a history of malignancy, with the exception of adequately treated or excised non metastatic basal cell or squamous cell cancer of the skin or cervical carcinoma in situ.
Subjects with specific laboratory test abnormalities
Subjects with specific types of infections

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