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Study Title Principal Investigator
Optimizing the Dose of Rehabilitation After Stroke.
Active, not recruiting | Stroke | Not Multisite
Carolee Winstein
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Magnesium Therapy: a Novel Platform for Neuroprotectant Sampling in Acute Stroke
Terminated | Stroke | Multisite
William Mack
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Neuroprotection In Patients Undergoing Aortic Valve Replacement
This is a multicenter randomized trial in which patients diagnosed with calcific aortic stenosis (AS) with planned AVR will be randomized to 1) the treatment arm of the Edwards Life Science filter and cannula or the filter as a stand alone with any cannula or 2) to the treatment arm of the CardioGard cannula versus 3) standard care in a 1:1:1 ratio.
Completed | Aortic Stenosis | Multisite
Annetine Gelijns
AtRial Cardiopathy and Antithrombotic Drugs In Prevention After Cryptogenic Stroke
ARCADIA is a multicenter, biomarker-driven, randomized, double-blind, active-control, phase 3 clinical trial of apixaban versus aspirin in patients who have evidence of atrial cardiopathy and a recent stroke of unknown cause. Eleven hundred subjects will be recruited over 2.5 years at 120 sites in the NINDS StrokeNet consortium. Subjects will be followed for a minimum of 1.5 years and a maximum of 4 years for the primary efficacy outcome of recurrent stroke and the primary safety outcomes of symptomatic intracranial hemorrhage and major hemorrhage other than intracranial hemorrhage.
Recruiting | Stroke | Multisite
Mitchell Elkind
Intra-arterial Magnesium Therapy: A Novel Platorm for Neuroprotectant Delivery in Acute Stroke
Terminated | Stroke | Multisite
William Mack
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