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Clinical Trials and Studies

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Contact us at (800) USC-CARE (800-872-2273)

Study Title Principal Investigator
Improving dermatologic care for psoriasis patients
We seek to evaluate an online psoriasis-care delivery model. Through this online model, patients can see the dermatologist online rather than coming into the office for a visit. The model is designed to increase patient and primary care physician access to dermatologists. We want to find out if this online model ultimately improves psoriasis severity and quality of life.
Not yet recruiting | psoriasis | Not Multisite
April W. Armstrong, MD MPH
View Research Profile
Tracking the Risk for Alzheimer’s Disease using the APT Webstudy
The Alzheimer Prevention Trials (APT) Webstudy is designed to accelerate enrollment into Alzheimer’s clinical trials by identifying and tracking individuals online, who may be at higher risk for developing Alzheimer’s. The Alzheimer’s Association estimates that 5.5 million Americans age 65 and older are currently living with Alzheimer’s dementia. It’s believed these numbers will increase by almost 30% to over 7 million people by 2025, where it’s the only top 10 cause of death that cannot be prevented, cured, or even slowed. The APT Webstudy is open to anyone over the age of 50. The goal of the APT Webstudy is to develop an online group of individuals who will allow their memory and thinking test scores to be tracked over time. Participants will have the opportunity to take online tests to assess their memory and thinking skills, gain access to their scores, and be notified of opportunities for in-person assessments and clinical trials aimed at preventing dementia. These in-person visits will be offered through the closest clinical site to participants.
Recruiting | alzheimer | Not Multisite
Paul Aisen, MD
New study seeks to understand how the brain optimizes walking in older adults
The purpose of this study is to understand how people control walking and balance. We are looking for healthy older adults who are interested in joining the study. Participants will walk on a treadmill while using an interactive display that will help them modify their walking pattern. We will determine how these modifications influence oxygen consumption during walking and measures of balance.  
Not yet recruiting | balance | Not Multisite
James Finley, PhD
Join today! New study at USC tests effectiveness of newly approved drug to help people with eczema, called Atopic Dermatitis
Atopic Dermatitis is a form of eczema that causes dry, scaly, itchy skin. More than 3 million cases are reported in the U.S. each year. People with this skin condition often have problems with bacterial skin infections caused by a specific bacteria known as, Staph aureus, or just Staph. Patients with chronic eczema often use long-term topical or oral treatments to help control their symptoms. But using these medications over long periods of time can have side effects on the body. The purpose of this study is to test the effectiveness of the drug dupilumab (dupixent), which was recently approved by the Food and Drug Administration (FDA) to offer relief to patients who cannot control their eczema with commonly used topical medications.We want to find out how dupilumab affects the amount of bacteria on the skin and the immune system of the patients, and whether it might cause less side effects. Join us today if you are between 18-65 years old with chronic eczema (Atopic Dermatitis).
Recruiting | eczema | Not Multisite
Peck Y. Ong, MD
A pilot study of safety and adequacy of pancreatic lesion biopsy (Spy Bite)
The purpose of this study is to determine the safety and effectiveness of an experimental technique to obtain biopsies of pancreatic lesions. This technique uses biopsy forceps, which are small jaw-like devices that open and close, to also obtain tissue samples for examination and diagnosis. The biopsy forceps will pass through the endoscope that is already in place for the endoscopic ultrasound guided fine needle aspiration procedure, and an additional biopsy will be taken. This technique is experimental because biopsy forceps are routinely used in gastrointestinal endoscopy, but are not routinely used to obtain biopsies of the pancreas.
Not yet recruiting | pancreatic cancer | Not Multisite
Jacques Van Dam, MD, PhD
View Research Profile
Testing a new drug to reduce anxiety and agitation in people with Alzheimer's disease and dementia
<p>A person with Alzheimer's often feels anxious or upset easily. They might be restless, unable to sleep or pace back and forth. These problems, called agitation, can keep them from a normal day-and-night routine and might become harmful for your loved one or their caregivers. </p><p>Can FDA-approved medication that treats sadness and anxiety also help with agitation? USC Alzheimer Disease Research Center is looking for volunteers with any form of dementia (Alzheimer's disease) to join our 24-week study of Escitalopram to reduce agitation. </p><p>Volunteers and their caregivers will receive structured and personalized resources and therapies. Participants will receive Escitalopram for 12 weeks, with in-person visits at weeks 3, 6, 9, and 12, and with telephone contacts between in-person visits.</p>
Not yet recruiting | Alzheimer's Disease | Not Multisite
Lon Schneider, MD
Suicide Risk - Mechanisms of Proximal Suicide Risk
<p>Suicide is the second leading cause of death among young adults in the United States. Some types of thinking patterns and feelings may differ in people with a history of depression and suicidal thoughts. However, not enough is known about how the brain influences the way people feel, like how people help themselves feel better. </p><p> The purpose of this study is to better understand how people’s thinking affects their feelings, and how this might be related to risk for (or protection against) suicidal thinking and behavior.</p>
Not yet recruiting | suicidal ideation | Not Multisite
Jonathan Stange
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