Transcranial Magnetic Stimulation and Psychotherapy for Treating Obsessive-Compulsive Disorder
This study will test how people with OCD respond to a type of noninvasive brain stimulation, repetitive Transcranial Magnetic Stimulation (rTMS), when it is combined with psychotherapy. Participants will either engage in Exposure and Response Prevention (ERP) Therapy or supportive therapy (ST) while receiving rTMS. Biobehavioral data from wearable devices and smartphones will be collected to better predict treatment responses. Participants will also undergo repeat resting state functional Magnetic Resonance Imaging (rsfMRI) in order to assess neural predictors and mechanisms of treatment response.
Study at USC is developing active sitting technology. Join today!
<p> Older adults can spend nearly 80% of their day sitting, doing sedentary activities such as watching TV, reading, and using the computer. FitSitt is an innovative device tailored to older adults and designed to improve health by increasing the convenience of breaking up sedentariness and incorporating movement into in-home daily routines. Whereas many interventions aim to increase physical activity by focusing on dedicated exercise sessions such as daily workouts, research suggests that key improvements to health can occur when regular movement is woven into the day, thereby reducing long inactive periods. </p><p> The purpose of this study is to refine and tailor a working prototype of FitSitt, and test the system to see if it is feasible to use and acceptable to older adults. This project will ultimately help the development of an optimized, in-home, comprehensive sedentary activity solution for older adults and countless other populations that could benefit from reducing the deleterious health effects of extended inactive behavior through convenient and comfortable-to-use intervention. </p>
Not yet recruiting | sedentary activity | Not Multisite
Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)
The goal of this clinical trial is to evaluate the effectiveness and safety of bilateral stimulation of the subcallosal cingulate white matter (SCCwm) using Deep Brain Stimulation (DBS) as an adjunctive treatment of non-psychotic unipolar Major Depressive Disorder (MDD) in adults.
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