Effect of Cold Stored Platelets to Slow or Stop Severe Internal Bleeding in Trauma Patients
<p style="text-align: center;"><span style="font-size: 18px;"><strong>Under the FDA rule Exception From Informed Consent (EFIC), severely injured patients taken to LAC+USC Medical Center with internal bleeding <u style="">may be enrolled into this clinical trial without their prior consent</u>. </strong><span style="font-size: 18px;"> </span></span></p><p style="text-align: left;">This site is to inform the public about this upcoming study and to give the public an opportunity to voice their opinion and/or to opt-out of the study in advance.</p><p style="text-align: left;"> </p><p style="text-align: center;">************</p><p style="text-align: left;">Trauma is the leading cause of death in people younger than 45 years. Unfortunately, 40-50% of severely injured patients with internal bleeding die, even after reaching the hospital. This clinical study is about whether Cold Stored Platelets can help slow or stop severe internal bleeding while the patient is being treated by the trauma team. </p><p style="text-align: left;">Platelet transfusions are a vital component of damage control resuscitation and are essential to blood clot formation and early stopping of severe bleeding. In usual care, platelets are stored in room temperature because they survive longer once infused into the body compared to cold-stored platelets. However, there are studies that suggest that cold-stored platelets can still be effective in early stopping of severe bleeding. This study is being done to see if giving Cold-Stored Platelets early in the course of treatment is feasible and if it would help improve outcomes in injured patients that lose a lot of blood.</p><p style="text-align: center;"><br></p><p style="text-align: center;">Scroll down to learn more.</p><p style="text-align: center;"> <br></p>
Help stroke survivors! Join research study on motion, balance and walking
<p> 85% of survivors of stroke experience walking issues, which limit their activities and participation. These issues include decreased coordination and slower walking, which might make people more prone to falls.</p><p> The objective of this study is to measure walking in people shortly after stroke and to identify which aspects of walking early after stroke indicate how well a patient recovers. Identifying these features will help physical therapists customize therapies to promote recovery of walking and help with other balance issues after a stroke. Therefore, we plan to test stroke survivors between 1-6 months after stroke and up to a year after they have suffered a stroke. </p>
All of Us Research Program
<p>The All of Us Research Program is a historic effort to gather information from one million or more people living in the United States. All of Us is a research program funded by the National Institutes of Health (NIH). The mission of the All of Us Research Program is to accelerate health research and medical breakthroughs, enabling individualized prevention, treatment, and care for all of us.</p><p><br></p>
CHLA Research Study on Cerebrovascular Impact of Acquired Anemia
Anemia is a condition where the body is not making enough red blood cells to transport oxygen. The objective of this study is to learn how anemia may affect the oxygen delivery to the brain as measured by magnetic resonance imaging (MRI). By studying this, we hope to better identify people who may benefit from correction of their anemia.
Healthy Fetal and Placental Development
A newborn is truly a miracle! In the mother's womb, many factors work together to ensure healthy development for the baby. Scientists and doctors at USC/Children's Hospital Los Angeles are trying to understand how a baby's development in the womb impacts its health across its life. This helps us provide better therapies and treatments for babies with birth defects so that they can lead healthy lives. <br>
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