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Clinical Trials and Studies

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Study Title Principal Investigator
CHLA Research Study on Neurovascular and Neurocognitive Consequences of Iron Deficiency Anemia
Anemia is a condition where the body is not making enough red blood cells to transport oxygen. The objective of this study is to learn how anemia may affect the oxygen delivery to the brain as measured by magnetic resonance imaging (MRI). By studying this, we hope to better identify people who may benefit from correction of their anemia by iron therapy.
Recruiting | anemia | Multisite
John C. Wood, MD, PhD
Exploring Life Events Prior to Death by Suicide
<p>We are interested in creating better means of suicide prevention. One way to do this is by discussing suicide with those who have lost a loved one. If you are a survivor of loss, we want to hear the story of your loved one. We believe that by investigating the experiences of an individual prior to their death, we can better understand important risks that are often overlooked in current suicide prevention efforts.&nbsp;</p><p> This information may help&nbsp;to build better connections to prevent others from going through this loss.&nbsp;&nbsp;</p>
Recruiting | suicide | Not Multisite
John Blosnich
RESTORE: WeaRablEs for Stroke FuncTiOn in the NatuRal Environment
<p>One of the most frequent consequences&nbsp;of a stroke is arm and hand motor impairment. In fact, more than 60% of stroke survivors&nbsp;have motor impairments on one side of the body, which may limit&nbsp;participation in everyday activities and quality of life.&nbsp;To date, only few studies look at what influences motor recovery, apart from capacity. </p><p>This study aims to better understand what&nbsp;influences how stroke survivors choose to use the more affected arm and hand&nbsp;in everyday activities, such as confidence in using the arm or positive social interactions. </p>
Not yet recruiting | stroke; rehabilitation; arm; health technology | Not Multisite
Carolee Winstein, BA, BS, MS, PhD
Development of an online mindfulness program for stroke survivors and their caregivers
This study aims to test the satisfaction and ease-of-use of an online mindfulness program. The program is&nbsp;specifically designed to increase mindfulness&nbsp;for stroke survivors&nbsp;and their caregivers or loved ones. We are particularly interested to obtain feedback&nbsp;on the content of the program&nbsp;and the website used to offer it. The feedback and suggestions will help us to&nbsp;create a final version that is easy to understand and relevant for stroke survivors and caregivers. This study will be done virtually (no face-to-face visit).&nbsp;
Not yet recruiting | stroke | Not Multisite
Carolee Winstein, BA, BS, MS, PhD
A Clinical Study of Patients With Symptomatic Neurogenic Orthostatic Hypotension to Assess Sustained Effects of Droxidopa Therapy
This is a multi-center, multi-national, randomized, parallel-group, placebo-controlled, double-blind study with a 17 week (maximum) treatment period consisting of an initial, open-label dose titration (up to 2 weeks), followed by a washout period (up to 3 weeks), followed by a 12 week treatment period on a stable dose.
Recruiting | Parkinson's Disease | Multisite
Horacio Kaufmann
201147: a Phase IIIb, Randomized, Open-label Study of the Safety, Efficacy, and Tolerability of Switching to a Fixed-dose Combination of Abacavir/Dolutegravir/ Lamivudine From Current Antiretroviral Regimen Compared With Continuation of the Current Antiretroviral Regimen in HIV-1 Infected Adults Who Are Virologically Suppressed, The STRIIVING Study.
Recruiting | AIDS / HIV | Multisite
GSK Trials
CHLA Research Study on Childhood Outcomes of Preterm Brain Abnormalities
<p>The purpose of this CHLA Research Study is to collect and compare information from your child's magnetic resonance imaging (MRI) scans, neurological exam and neuropsychological assessments. We hope to find whether there is a specific pattern of brain changes associated with prematurity that will help with early screening, diagnosis, and treatment of brain injury in prematurely born children as well as identify a connection between MR imaging and neurodevelopmental outcomes.</p>
Recruiting | premature | Not Multisite
Natasha Lepore, PhD
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