Lupus patients on Twitter: What do they think about using Twitter to engage them with their health?
It is estimated that at least 5 million Americans have the autoimmune disease lupus, with more than 16,000 new cases of lupus being reported annually in the U.S. Many patients take to Twitter to share their disease experience. With this study, we want to better understand Lupus patients who use Twitter and hear from them whether Twitter could be used as a tool to engage them with healthcare and research. This study is restricted to Lupus patients on Twitter who were contacted by the study team.
Tracking Obsessive-Compulsive Disorder (OCD) symptoms and predicting response to treatment using Fitbit, neuroimaging, and smartphone surveys.
<p>Obsessive-Compulsive Disorder (OCD) is a chronic, impairing disorder characterized by unwanted obsessions and/or compulsions. Not all persons with OCD are alike, resulting in a wide variety of symptoms, illness course, and response to treatment. The purpose of our OCD research study is to better understand differences in OCD symptoms and to predict both illness course and response to treatment. By comparing data from participants with OCD and healthy volunteers without OCD, we hope to provide enhanced treatments to future patients.</p>
Investigating efficacy and safety of adjunctive therapy in Parkinson’s Disease patients
Parkinson’s Disease involves the loss of brain cells that produce dopamine, a messenger that sends information to the parts of the brain that control movement and coordination. Lower than normal levels of dopamine in the brain causes the symptoms of Parkinson’s, including muscle stiffness, resting tremor (uncontrollable shaking), and slowing of movements. Parkinson’s patients may have “on” periods where they are able to control their muscle movement, and “off” times when controlling these movements is harder.
Levodopa is a medication used to help treat Parkinson’s by increasing dopamine levels in the brain. We are looking for participants who have these “on” and “off” periods, and who are on Levodopa and at least one other medication. We are looking at whether adding tozadenant, a drug that hasn’t been approved by the U.S. FDA, will help improve Parkinson’s symptoms.
Recruiting | parkinsons adjunctive therapy | Not Multisite
Assessing the safety and efficacy of Macitentan in patients with portopulmonary hypertension
Several drugs (blood vessel dilators), including macitentan, are currently approved for the treatment of pulmonary arterial hypertension (PAH) in many parts of the world. These drugs have significantly improved the outcome of the condition. However, none of these treatments have been evaluated in portopulmonary hypertension, a form of PAH caused by liver disease. The purpose of this study is to assess the safety and effectiveness of macitentan in portopulmonary hypertension by looking at several clinical indicators, including the pressures within the arteries of the lungs and a person’s capacity for exercise.
Recruiting | High Blood Pressure / Hypertension | Not Multisite
How does a stroke affect balance during walking?
<p>The purpose of this study is to understand how a stroke affects walking balance and why people post-stroke fall more frequently. Findings from this study could inform the design of rehabilitation interventions to improve post-stroke walking ability.</p><p><strong>We are looking for</strong> <strong>people who have had a stroke AND healthy adults who have not had a stroke. </strong>Participants will walk on a treadmill while experiencing trips that challenge balance, but a safety harness will be worn to prevent any falls.</p>
USC GeneScreen: The USC Alzheimer’s Prevention Registry
<p>Researchers at USC invite you, and your friends and family, to <u>enroll online</u> in USC GeneScreen, USC Alzheimer's Prevention Registry.</p><p>Alzheimer’s disease is a brain disease that affects memory, thinking, and behavior. It is a progressive brain disorder that causes severe memory loss over time, making it increasingly difficult for people to carry out daily activities. Alzheimer's disease impacts us all. </p><p> While valuable Alzheimer's research is being done every day to treat and prevent this disease, finding interested research participants remains an ongoing challenge. USC GeneScreen is a registry for people who are interested in participating in Alzheimer’s disease research studies at USC. By joining the registry, members are the first to hear about new and innovative studies that they may be eligible to participate in. </p>
Tracking the Risk for Alzheimer’s Disease using the APT Webstudy
The Alzheimer Prevention Trials (APT) Webstudy is designed to accelerate enrollment into Alzheimer’s clinical trials by identifying and tracking individuals online, who may be at higher risk for developing Alzheimer’s. The Alzheimer’s Association estimates that 5.5 million Americans age 65 and older are currently living with Alzheimer’s dementia. It’s believed these numbers will increase by almost 30% to over 7 million people by 2025, where it’s the only top 10 cause of death that cannot be prevented, cured, or even slowed. The APT Webstudy is open to anyone over the age of 50. The goal of the APT Webstudy is to develop an online group of individuals who will allow their memory and thinking test scores to be tracked over time. Participants will have the opportunity to take online tests to assess their memory and thinking skills, gain access to their scores, and be notified of opportunities for in-person assessments and clinical trials aimed at preventing dementia. These in-person visits will be offered through the closest clinical site to participants.
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