Cognition as a moderator of motor learning post-stroke


The goal of this study is to understand how an individual’s cognitive function and brain structure may influence their ability to learn a new walking pattern. We hope to learn how people can best learn a new walking pattern when parts of the brain are damaged and cognitive function may be impaired.

We are looking for survivors of stroke, 6 months or more after their stroke, who can walk on a treadmill for at least 5 minutes.

Keywords: stroke, cognition, brain, walking, motor learning

Study Sites

1540 Alcazar St. CHP 155, Los Angeles, CA 90033

  • Men & Women
Age icon
45 - 85

What's involved?

Study length
  • 2 weeks

Number of visits
  • 2 visits, each lasting 3-4 hours

  • none

  • Walking and balance assessments

  • Cognitive assessments

  • Walking on a treadmill

  • Compensation is available for each study visit.

Medical cost coverage
  • Study-related tests and procedures are covered.

Why participate?

Contribute to developing more effective walking interventions for persons post-stroke.


Must have

  • Age 45-85
  • >6 months post stroke
  • Stroke on one side of the brain
  • Weakness on one side only
  • Able to walk independently (including use of assistive devices)
  • Able to walk 5 minutes without stopping
  • Answers "no" to all general health questions on telephone screening

Can't have

  • Stroke in the brainstem or cerebellum
  • Aphasia (difficulty speaking or understanding speech)
  • Any condition that may impact ability to complete assessment of sensorimotor cognitive function
  • Uncontrolled high blood pressure
  • Significant cognitive deficit or dementia
  • Inability to give informed consent

About This Study

As many as 70% of older adults with chronic stroke have post-stroke cognitive impairment. Our study aims to assess the impact of post-stroke cognitive impairment on motor learning during walking. With this information, we hope to help guide rehabilitation and individually tailor treatments to improve walking function in those with chronic stroke.

Study Team

Principal Investigator
Kristan Leech

For questions about this study, contact:

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