The Genetics of Liver Fat (GoLF): Contributions of Genes and Liver Fat to Diabetes Risk in Mexican Americans


Diabetes affects millions of people in the United States, and Latinos are at higher risk. The liver plays an important role in regulating blood sugar. At the University of Southern California (USC), we are seeking participants for an ongoing study to investigate how differences in your genes impact liver fat levels, and how these levels affect diabetes risk. We want to improve the understanding of diabetes, obesity, and fatty liver disease, and work toward developing better ways to treat and prevent these diseases.

This is a collaborative study between Kaiser Permanente Southern California (KPSC) and the University of Southern California (USC), sponsored by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).

Over 100 million adults in the U.S. are living with diabetes or prediabetes, and Latinos are at higher risk than other groups.  Participate in the USC Genetics of Liver Fat Study (GoLF) today and let's work together towards better solutions for treatment and prevention!

Keywords: Diabetes Type 2, Fatty Liver Disease, Blood Sugar, Mexican, Mexican-American, Genes

Study Sites

University of Southern California, Health Sciences Campus, 2250 Alcazar St, Los Angeles, CA 90033

  • Men & Women
Age icon
18 +

What's involved?

Study length
  • 4 weeks

Number of visits
  • 3

  • No medication

  • Glucose Tolerance Tests

  • Magnetic Resonance Imaging (MRI)

  • Health Questionnaires

  • Physical Exam

  • Blood Tests

  • Body Composition Scan

  • Participants will be compensated for each study visit

Medical cost coverage
  • There are no medical costs to participants

Why participate?

Let's work together to push critical public health research forward!


Must have

  • 18 years or older
  • Mexican or Mexican-American
  • Not diabetic

Study Team

Principal Investigator
Richard M Watanabe, PhD
Principal Investigator
Thomas A Buchanan, MD
Principal Investigator
Anny H. Xiang, PhD

For questions about this study, contact:

  • Dr. Enrique Trigo
  • University of Southern California, Health Sciences Campus, 2250 Alcazar St, Los Angeles, CA 90033
  • (323) 313-2741

Research study materials

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