The number of people who vape and use e-cigarettes has been increasing, particularly among young adults. We want to examine how factors associated with vaping and e-cigarette use, such as flavoring and nicotine level, effect people's thoughts, feelings, and behaviors. If you participate in this study, we will ask you to complete...
The STRIDE study is a prospective, multi-center, randomized, controlled trial of the eShunt System in the treatment of patients with normal pressure hydrocephalus.
This is an open label, multi-center, single arm phase II study. The study will investigate the efficacy of sodium cridanimod in conjunction with progestin therapy in a population of patients with recurrent or persistent PrR-negative endometrial cancer. Eligible patients will be enrolled into the study and administered sodium cridanimod in...
The number of people who vape and use e-cigarettes has been increasing, particularly among young adults. We want to examine how factors associated with vaping and e-cigarette use, such as flavoring and nicotine level, effect people's thoughts, feelings, and behaviors.
Anemia is a condition where the body is not making enough red blood cells to transport oxygen. The objective of this study is to learn how anemia may affect the oxygen delivery to the brain as measured by magnetic resonance imaging (MRI). By studying this, we hope to better identify...
This is a multi-center, multi-national, randomized, parallel-group, placebo-controlled, double-blind study with a 17 week (maximum) treatment period consisting of an initial, open-label dose titration (up to 2 weeks), followed by a washout period (up to 3 weeks), followed by a 12 week treatment period on a stable dose.
The purpose of this CHLA Research Study is to collect and compare information from your child's magnetic resonance imaging (MRI) scans, neurological exam and neuropsychological assessments. We hope to find whether there is a specific pattern of brain changes associated with prematurity that will help with early screening, diagnosis, and...
85% of survivors of stroke experience walking issues, which limit their activities and participation. These issues include decreased coordination and slower walking, which might make people more prone to falls.
The objective of this study is to measure walking in people shortly after stroke and to identify which aspects...
The All of Us Research Program is a historic effort to gather information from one million or more people living in the United States. All of Us is a research program funded by the National Institutes of Health (NIH). The mission of the All of Us Research Program is to accelerate health research and medical breakthroughs,...
Anemia is a condition where the body is not making enough red blood cells to transport oxygen. The objective of this study is to learn how anemia may affect the oxygen delivery to the brain as measured by magnetic resonance imaging (MRI). By studying this, we hope to better identify...
A newborn is truly a miracle! In the mother's womb, many factors work together to ensure healthy development for the baby. Scientists and doctors at USC/Children's Hospital Los Angeles are trying to understand how a baby's development in the womb impacts its health across its life. This helps us provide...
The goal of this study is to understand how an individual’s cognitive function and brain structure may influence their ability to learn a new walking pattern. We hope to learn how people can best learn a new walking pattern when parts of the brain are damaged and cognitive function may...
The Healthy Minds Volunteers (http://healthyminds.usc.edu) help research labs at the University of Southern California. These labs are working towards a greater understanding of how aging can affect physical, mental and emotional health. The goal is to learn how we can maintain healthy minds and bodies across our lifespan.
The purpose of this study is to track active VNS Therapy treatment in subjects with Treatment-Resistant Depression (TRD) and to better understand the reduction in the severity of baseline TRD symptoms. Data will be collected on your responses to study treatments, quality of life, productivity, and your use of healthcare services. Your...
We are seeking pregnant adults to participate in a study evaluating a novel, quieter MRI scanner. We hope to develop better ways for doctors to screen pregnancies for possible fetal problems and to make MRI of unborn babies more comfortable and even safer. Images will be collected at 3-6 fold...
The main goal of medical management of Urea Cycle Disorder (UCD) patients is to prevent chronic or acute hypperammonemic states leading to central nervous damage- which requires a restriction in dietary protein intake and using nitrogen scavenging agents if diet alone does not help the patients.The objective of this study...
Transcatheter aortic valve implantation (TAVI) has become a routine treatment option at specialized heart centers treating patients with severe aortic stenosis who are at high risk for surgical aortic valve replacement (SAVR). Medtronic has developed modifications to the Medtronic CoreValve System Transcatheter Aortic Valve frame and delivery catheter system to...
The goal of this study is to better understand how brain functioning relates to mood and eating behaviors in real life. You may be eligible if you experience binge eating or have difficulties controlling your eating behavior.
