The purpose of this study is to understand how people control walking and balance. We are looking for healthy older adults who are interested in joining the study. Participants will walk on a treadmill while using an interactive display that will help them modify their walking pattern. We will determine how these modifications...
The purpose of this study is to determine the safety and effectiveness of an experimental technique to obtain biopsies of pancreatic lesions. This technique uses biopsy forceps, which are small jaw-like devices that open and close, to also obtain tissue samples for examination and diagnosis. The biopsy forceps will pass...
The purpose of this study is to evaluate the safety and effectiveness of a procedure using the RECELL® System for repigmentation of stable vitiligo. Stable vitiligo means that for at least 12 months:
• Areas affected by loss of pigment have not increased in size.
• No new areas with...
Do any of your friends, family, or loved ones have problems remembering or have developed Alzheimer’s disease? The USC Alzheimer Disease Research Center is testing how well a drug may help to prevent the loss of memory. The research team is looking for volunteers (ages 60 to 75) who do...
A person with Alzheimer's often feels anxious or upset easily. They might be restless, unable to sleep or pace back and forth. These problems, called agitation, can keep them from a normal day-and-night routine and might become harmful for your loved one or their caregivers.
Can FDA-approved medication that treats...
This is an open label, multi-center, single arm phase II study. The study will investigate the efficacy of sodium cridanimod in conjunction with progestin therapy in a population of patients with recurrent or persistent PrR-negative endometrial cancer. Eligible patients will be enrolled into the study and administered sodium cridanimod in...
This is a multi-center, multi-national, randomized, parallel-group, placebo-controlled, double-blind study with a 17 week (maximum) treatment period consisting of an initial, open-label dose titration (up to 2 weeks), followed by a washout period (up to 3 weeks), followed by a 12 week treatment period on a stable dose.
Under the FDA rule Exception From Informed Consent (EFIC), severely injured patients taken to LAC+USC Medical Center with internal bleeding may be enrolled into this clinical trial without their prior consent.
This site is to inform the public about this upcoming study and to give...
85% of survivors of stroke experience walking issues, which limit their activities and participation. These issues include decreased coordination and slower walking, which might make people more prone to falls.
The objective of this study is to measure walking in people shortly after stroke and to identify which aspects...
The All of Us Research Program is a historic effort to gather information from one million or more people living in the United States. All of Us is a research program funded by the National Institutes of Health (NIH). The mission of the All of Us Research Program is to accelerate health research and medical breakthroughs,...
Anemia is a condition where the body is not making enough red blood cells to transport oxygen. The objective of this study is to learn how anemia may affect the oxygen delivery to the brain as measured by magnetic resonance imaging (MRI). By studying this, we hope to better identify...
Trauma is the leading cause of death in people younger than 45 years. Unfortunately, 40-50% of severely injured patients with internal bleeding die, even after reaching the hospital. This clinical study is about whether ResQFoam can help slow or stop severe internal bleeding in the abdomen (belly area) while the...
The goal of this study is to understand how an individual’s cognitive function and brain structure may influence their ability to learn a new walking pattern. We hope to learn how people can best learn a new walking pattern when parts of the brain are damaged and cognitive function may...
The Healthy Minds Volunteers (http://healthyminds.usc.edu) help research labs at the University of Southern California. These labs are working towards a greater understanding of how aging can affect physical, mental and emotional health. The goal is to learn how we can maintain healthy minds and bodies across our lifespan.
The purpose of this study is to track active VNS Therapy treatment in subjects with Treatment-Resistant Depression (TRD) and to better understand the reduction in the severity of baseline TRD symptoms. Data will be collected on your responses to study treatments, quality of life, productivity, and your use of healthcare services. Your...
We are seeking pregnant adults to participate in a study evaluating a novel, quieter MRI scanner. We hope to develop better ways for doctors to screen pregnancies for possible fetal problems and to make MRI of unborn babies more comfortable and even safer. Images will be collected at 3-6 fold...
The primary objective of this study is to study the effectiveness of a novel targeted immune therapy (biologic) called LY3074828 in treating moderate to severe ulcerative colitis. This study will take place over 120 weeks and all study visits and procedures will be provided at no cost to you. During...
The main goal of medical management of Urea Cycle Disorder (UCD) patients is to prevent chronic or acute hypperammonemic states leading to central nervous damage- which requires a restriction in dietary protein intake and using nitrogen scavenging agents if diet alone does not help the patients.The objective of this study...
Transcatheter aortic valve implantation (TAVI) has become a routine treatment option at specialized heart centers treating patients with severe aortic stenosis who are at high risk for surgical aortic valve replacement (SAVR). Medtronic has developed modifications to the Medtronic CoreValve System Transcatheter Aortic Valve frame and delivery catheter system to...
Alzheimer’s disease is a brain disease that affects memory, thinking, and behavior, and causes severe memory loss over time, known as dementia. Diabetes increases the risk of developing Alzheimer’s disease and related dementias. Latinos have a higher risk of developing both diabetes and Alzheimer's but are underrepresented in research. We are studying...
A prospective multicenter randomized blinded study comparing Aquablation of the prostate with the AQUABEAM System and TURP for the treatment of Lower Urinary Tract Symptoms (LUTS). The primary endpoints for safety and effectiveness will be measured at 3 and 6 months, respectively, and subjects will be followed out to 3...
What does this study focus on?
Cannabis is the most commonly used substance during pregnancy, yet little is known about why women use cannabis use during pregnancy.
What is the goal of this study?
The goal of this study is to talk and listen to Black, Indigenous, and People of Color (BIPOC) women who...
